Hpv vaccine side effects

Hpv vaccine side effects

External genital warts and their associated HPV infections are considered among the most common sexually transmitted diseases affecting the general population. It is estimated that one percent of the sexually active population of the United States, or 3 to 6 million people, acquire symptomatic genital wart infections each year. Approximately 90 percent of genital warts are related to infection with HPV subtypes 6 and 11, which have a very low malignant potential and rarely progress to cancerous lesions. However, those warts associated with HPV subtypes 16 and 18 may be predisposed to oncogenic transformation.

Current treatment options focus predominantly on removal of the external wart rather than attacking the underlying viral infection and have thus proven somewhat inadequate in achieving effective long-term results. Therapies can be categorized as topical, surgical, or immunomodulatory and can differ quite significantly in terms of cost, duration of therapy, dosing schedules, and adverse effects. As of yet, there is little evidence to suggest that one class of treatments is not more effective than another nor has a single therapy emerged as the gold standard for treatment. Selection of a therapeutic modality typically depends on the needs and desires of the individual patient.

Hpv vaccine effectiveness

Given the strikingly high prevalence of genital warts among the population, and the lack of adequate therapies, HPV vaccines such as HPV4 and HPV2 may play a significant role in reducing the burden of disease by preventing viral infection and transmission. Studies evaluating the effectiveness of HPV vaccines in preventing genital wart infection have shown it to be both safe and extremely successful in both sexes.

This supports the need for further research into the development of similar vaccines targeting additional subtypes of HPV. As vaccination against HPV continues to gain popularity and a broader therapeutic population base, it may prove to be instrumental in the treatment and eventual eradication of genital warts.



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